Polypoidal Choroidal Vasculopathy in Highly Myopic Eyes with Elongated Axial Length
نویسندگان
چکیده
Purpose To retrospectively review the prevalence of myopia and elongated axial length in eyes with polypoidal choroidal vasculopathy (PCV) and to evaluate treatment response of PCV in highly myopic eyes. PCV has rarely been reported in myopic eyes. Methods A retrospective review of all eyes diagnosed with PCV at the clinics of Retina Consultants of Hawaii and the Hawaii Macula and Retina Institute was performed between February of 2007 and April of 2017 to evaluate for eyes with significant myopia and elongated axial length. Results A total of 282 eyes were diagnosed with PCV by ICG angiography. There were 144 males (59%) and 99 females (41%). 204 patients had unilateral PCV and 39 patients had bilateral PCV. A total of 3 patients with PCV had significant myopia less than -6 diopters or confirmed elongated axial length. One of these patients had bilateral PCV so there were 4 eyes noted with significant myopia and elongated axial length out of 282 eyes with PCV (1.4%). All 3 patients were Asian and presented with active leakage or bleeding related to PCV diagnosed on indocyanine green angiography and optical coherence tomography. Treatments typically used to treat PCV including intravitreal antiangiogenic medications and photodynamic therapy were utilized. Conclusion and Importance High myopia is rare in eyes diagnosed with PCV, even though choroidal neovascularization is a common cause of vision loss in myopic macular degeneration. However, even in highly myopic eyes, PCV may show signs of resistance to antiangiogenic medications.
منابع مشابه
Axial length changes in highly myopic eyes and influence of myopic macular complications in Japanese adults
PURPOSE To investigate changes of the axial length in normal eyes and highly myopic eyes and influence of myopic macular complications in Japanese adults. STUDY DESIGN Retrospective longitudinal case series. METHODS The changes in the axial length of 316 eyes from 316 patients (mean age, 63.8 ± 9.0 years; range, 34-82; 240 females) examined using IOLMaster with a follow-up period of at leas...
متن کاملIdiopathic polypoidal choroidal vasculopathy in Japanese patients.
OBJECTIVE To describe the vascular nature and clinical features of idiopathic polypoidal choroidal vasculopathy in Japanese patients. METHODS Patients thought to have idiopathic polypoidal choroidal vasculopathy were examined with binocular ophthalmoscopy, slitlamp biomicroscopy with a contact lens, fluorescein angiography, and indocyanine green angiography. RESULTS From January 1993 to Dec...
متن کاملProspective clinical trial of Intravitreal aflibercept treatment for PolypoIdal choroidal vasculopathy with hemorrhage or exudation (EPIC study): 6 month results
BACKGROUND Polypoidal choroidal vasculopathy is a variant of choroidal neovascularization and neovascular age related macular degeneration presenting with hemorrhagic and exudative changes within the macula and/or peripapillary region leading to vision loss. In contrast to neovascular age related macular degeneration, polypoidal choroidal vasculopathy has differing clinical manifestations and t...
متن کاملVariation in subfoveal choroidal thickness in patients with high myopia complicated by choroidal neovascularization
The aims of this study was to observe the variation in subfoveal choroidal thickness (SFCT) in patients with highly myopic macular complicated by choroidal neovascularization (CNV) and to compare choroidal thickness in these eyes with highly myopic eyes without CNV, matched with the others group by ages, genders, eye axial length and diopter. 72 cases with 72 eyes, confirmed with high myopia in...
متن کاملChoroidal thickness after intravitreal ranibizumab injections for choroidal neovascularization
PURPOSE To study changes in choroidal thickness with ranibizumab treatment for choroidal neovascularization (CNV). DESIGN Prospective case series. METHODS This prospective study consisted of 60 CNV-affected eyes of 60 patients treated with intravitreal injections of ranibizumab using an on-demand protocol after an initial loading phase. The eyes studied included 20 with age-related macular ...
متن کامل